GENE ONLINE|News &
Opinion
Blog

2018-10-05| Startups

Cambridge startup, GO Therapeutics make $195 million deal with Roche

by Rajaneesh K. Gopinath
Share To

This agreement grants Roche exclusive license for antibodies generated against novel cancer-specific targets and to develop a new glycotargeting bispecific antibody.

By Rajaneesh K Gopinath

GO Therapeutics Inc. (GO), an immuno-oncology startup company headquartered at Cambridge was founded in 2014. It applies new advances in glycoproteomics to develop potent, yet toxic free cancer therapeutics that are antibody-based. On October 2nd, the company announced that it has entered into a license agreement with Roche. This collaboration would facilitate the entry of its drug into the clinic by 2020. According to this agreement, Roche will pay GO $9 million upfront and the remaining $186 million in milestone payments. On top of this, GO would also receive royalties on any future product sales.

Constantine Theodoropulos, the chief executive officer of GO Therapeutics expressed his excitement over the deal. “We are excited about this collaboration to develop an innovative immune-redirected therapy to potentially improve the lives of patients suffering from cancer in the future,” he said in a statement. “GO’s glycoprotein targeting platform opens an exciting class of tumor-specific antigens that can help widen the therapeutic window for cancer therapies such as T-cell bispecific antibodies, CAR-T and ADCs (Antibody Drug Conjugates). Preclinical data show GO’s approach can provide superior specificity in targeting solid tumors over normal tissue, and demonstrate clean in-vivo toxicity profiles in the context of potent immunotherapies.”

Roche is expected to begin clinical trials on the licensed drug candidate in 2020, with GO starting clinical trials on its own drug candidate next year. GO is also developing a pipeline of other antibodies targeted against lymphomas, glioblastomas, liver, kidney and lung cancer tumors.

References

  1. http://gotherapeutics.com/2018/10/go-therapeutics-enters-into-a-license-agreement-with-roche-for-new-glycotargeting-bispecific-cancer-treatment/
  2. https://www.bizjournals.com/boston/news/2018/10/02/cancer-startup-go-therapeutics-eyes-clinic-after.html

 

©www.geneonline.com All rights reserved. Collaborate with us: [email protected]
Related Post
Roche Announces Massive 50 Billion Dollar Investment in the United States
2025-04-25
Layoffs in Biotech and Pharma: A February 2025 Overview by Therapeutic and Technology Focus
2025-04-01
Singapore’s A*STAR Invests in HoneyBear, Accelerating ARC Cancer Drug Development
2025-03-28
LATEST
AACR Annual Meeting 2025: Cancer Research Innovations, NIH Funding Advocacy, and AI-Driven Advances
2025-04-28
Senti Biosciences to Showcase New Cell & GeneTherapy Data at AACR Annual Meeting 2025
2025-04-27
World Vaccine Congress Washington 2025 Recap: Urgent Calls for Trust, Tech, and Global Access
2025-04-25
Astellas’ Transformation Journey: From Merger to Global Player, Betting on the Edge of Innovation and Risk?
2025-04-25
Roche Announces Massive 50 Billion Dollar Investment in the United States
2025-04-25
Steminent Stands Ready to Showcase Novel MSC-based Therapy for Spinocerebellar Ataxia at Global Stage
2025-04-24
Arkansas Medicaid Work Requirements Led to Coverage Loss for a Significant Number of Recipients
2025-04-24
EVENT
2025-04-25
AACR Annual Meeting 2025
Chicago, U.S.A
2025-05-03
29th Taiwan Joint Cancer Conference 2025
Taipei, Taiwan
2025-05-05
Swiss Biotech Day 2025
Basel, Switzerland
2025-05-13
ASGCT 28th Annual Meeting 2025
New Orleans, U.S.A.
2025-05-30
ASCO Annual Meeting 2025
Chicago, U.S.A
2025-06-11
ISSCR 2025 Annual Meeting
Hong Kong
Scroll to Top