Cannabis and Tobacco Combo Linked to Elevated Psychosis Risk in Vulnerable Individuals: Nature Mental Health Study

A new study published in Nature Mental Health reveals a significant link between the combined use of cannabis and tobacco and an elevated risk of psychosis in individuals already at high clinical risk for psychotic disorders. The multisite investigation, led by Dr. Heather Ward, examined the psychiatric implications of using both substances concurrently.

The research focused on individuals with a pre-existing high risk for developing psychotic disorders like schizophrenia. The findings indicate that the combined use of cannabis and tobacco significantly exacerbates the risk of psychosis in this vulnerable population. The study highlights the need for further research into the specific mechanisms by which these substances interact to increase psychiatric risks.

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Date: May 13, 2026

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