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2025-04-14| Asia PacificChina

China’s Biotech Industry Is Having Its Moonshot Moment

by Bernice Lottering
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China is producing first-in-class biologics, leading research in key areas such as VEGF x PD-1 combinations for solid tumors, and rapidly expanding its role in the global drug discovery pipeline.

China’s biotech industry is gaining speed—and global attention. Once considered a follower in pharmaceutical innovation, China now moves to the front of the pack, outpacing many U.S. firms in both development speed and cost-efficiency. Much like its rise in artificial intelligence, China’s biotech sector is advancing by innovating under pressure, backed by regulatory shifts and a deep, skilled talent pool.

Just four years ago, Chinese firms accounted for less than 5% of major pharmaceutical transactions. By 2024, that figure has surged to nearly 30%, according to DealForma. At this pace, many drugs entering the U.S. market a decade from now could very well originate in Chinese labs.

A defining moment came last fall, when Summit Therapeutics, backed by billionaire Bob Duggan, announced that its lung cancer drug outperformed Merck’s blockbuster Keytruda in a head-to-head trial. Keytruda, an immunotherapy heavyweight with $30 billion in annual sales, has long dominated the market. But Summit’s surprising win wasn’t just about the data—it was also about the drug’s origin. Licensed just two years prior from China’s Akeso, the drug’s success marked a seismic shift in global pharma dynamics.

Innovation and Speed Define China’s Edge

Several factors continue to fuel China’s rapid biotech ascent. Many of its top scientists, trained in American research labs, returned home after hitting career roadblocks in the West. They channeled their knowledge into building lean, innovation-driven companies in emerging biotech hubs like Shanghai and Beijing.

Chinese firms operate with fewer layers of management, faster decision-making, and lower overhead costs compared to their U.S. counterparts. Clinical trials in China also cost a fraction of those in the United States, allowing companies to move swiftly through development pipelines.

At the heart of this momentum lies strategic thinking. Chinese biotech companies focus heavily on improving existing drugs, modifying molecules to enhance efficacy or reduce side effects. It’s a model seen in China’s AI industry as well—where companies like DeepSeek created competitive chatbots despite limited access to high-end semiconductors.

Global pharmaceutical companies have taken notice. Many now consider licensing molecules from China rather than acquiring inflated U.S. biotech startups. The strategy not only reduces costs but also taps into a pipeline increasingly filled with first-in-class biologics and advanced candidates.

A Shifting Global Pharma Landscape

This surge in Chinese innovation is reshaping the pharmaceutical industry. China is now driving research in areas such as VEGF x PD-1 combinations, a promising oncology treatment, and continues to lead in developing first-in-class biologics. Between 2023 and 2024, nearly one-third of all licensed drug candidates came from Chinese firms—a striking indicator of the country’s growing influence.

Even with legislative pushback like the BIOSECURE Act, aimed at reducing U.S. reliance on Chinese biomanufacturing, resistance is building. Critics argue the proposed restrictions offer little national security benefit and risk undermining a supply chain the global industry now depends on.

At the same time, India is stepping onto the field, introducing another wave of competitive pressure. While the U.S. has historically led the biotech world—with innovation hubs like Boston and San Francisco drawing talent from elite institutions such as MIT and Stanford—it now faces a new reality. Costs are climbing, bureaucratic delays are mounting, and the efficiency edge once owned by American firms is slipping.

What This Means for Investors, Companies, and Patients

China’s momentum is creating ripple effects across the entire biotech ecosystem. For Western venture capitalists, the rise of lower-cost, higher-quality drug development out of China challenges the longstanding model of funding high-valuation U.S. biotechs. Investors must now weigh whether U.S. companies can continue to justify their price tags when viable—and sometimes superior—alternatives are emerging abroad.

Still, for patients, the outlook is promising. More competition typically leads to greater drug accessibility and affordability. Cancer patients, in particular, care most about outcomes—not where a drug was developed. With global innovation on the rise, more effective treatments are reaching the market faster and more affordably.

Looking Ahead: The Global Race Continues

China’s progress in biotech mirrors its advancements in other sectors like electric vehicles, drones, and robotics. These industries show that China can innovate under constraints while disrupting traditional leaders. Restrictive trade policies may slow, but won’t stop, this growth.

Meanwhile, the U.S. still holds significant advantages, particularly in financial infrastructure, legal protections, and capital markets. But long-term success will hinge on embracing open competition and doubling down on innovation—not protectionism.

The global race for biotech leadership is far from over. To stay ahead, U.S. firms will need to evolve, adopt leaner models, and collaborate more strategically. In the end, open markets and innovation—not borders—will determine the best outcomes for businesses, investors, and patients worldwide.

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