GENE ONLINE|News &
Opinion
Blog

2021-10-31| In-DepthSpecial

Combination of Essential Amino Acids Prevents Brain Atrophy in Dementia

by Manju Bhaskar
Share To
Recent studies in nutritional epidemiology have shown that protein malnutrition is a potential risk factor for senile dementia. Elderly people with dementia have lower protein intake than their healthy counterparts, which raises the risk of mild cognitive impairment and amyloid β accumulation in the brain.

Lower blood levels of essential amino acids (EAAs) are associated with the development of Alzheimer’s Disease (AD). Earlier scientists had found that chronic intake of ‘Amino LP7’ – a specific EAA composition—Leu, Phe, and Lys supplemented with Ile, His, Val, and Trp down-regulated the expression of synaptic components and a modest acceleration of brain atrophy in mice modeling neurodegenerative tauopathies.

In a new study, researchers investigated the association between the intake of dietary proteins/Amino LP7 and elements of the etiological cascade, including fibrillary tau depositions, neuroinflammation, abnormal neurotransmission, synaptic impairment, and neuronal loss in rTg4510 mice, a mouse model of tauopathy. The findings highlight the importance of specific amino acids as systemic mediators of brain homeostasis against neurodegenerative processes.

GO Prime with only $1.49 now

LATEST
Ginkgo Bioworks and Pfizer Forge $331 Million Collaboration for RNA-Based Drug Discovery
2023-09-29
Johnson & Johnson Partners with Singapore to Boost Life Sciences Innovation
2023-09-28
Vietnam and South Korea Strengthen Cooperation in Multiple Sectors
2023-09-27
PeptiDream and Genentech Collaborate on Novel Peptide-Radioisotope Drug Conjugates
2023-09-27
AcuraStem and Takeda Collaborate on Innovative ALS Treatment
2023-09-27
Seven AI/ML for Life Sciences Companies Identified as Innovators in New Clarivate Companies to Watch Report
2023-09-27
GeneOnline’s Weekly News Highlights: Sept 17-Sept 22
2023-09-26
EVENT
2023-10-04
BioFuture 2023
New York city,USA
Scroll to Top