GENE ONLINE|News &
Opinion
Blog

2021-10-31| In-Depth

Combination of Essential Amino Acids Prevents Brain Atrophy in Dementia

by Manju Bhaskar
Share To
Recent studies in nutritional epidemiology have shown that protein malnutrition is a potential risk factor for senile dementia. Elderly people with dementia have lower protein intake than their healthy counterparts, which raises the risk of mild cognitive impairment and amyloid β accumulation in the brain.

Lower blood levels of essential amino acids (EAAs) are associated with the development of Alzheimer’s Disease (AD). Earlier scientists had found that chronic intake of ‘Amino LP7’ – a specific EAA composition—Leu, Phe, and Lys supplemented with Ile, His, Val, and Trp down-regulated the expression of synaptic components and a modest acceleration of brain atrophy in mice modeling neurodegenerative tauopathies.

In a new study, researchers investigated the association between the intake of dietary proteins/Amino LP7 and elements of the etiological cascade, including fibrillary tau depositions, neuroinflammation, abnormal neurotransmission, synaptic impairment, and neuronal loss in rTg4510 mice, a mouse model of tauopathy. The findings highlight the importance of specific amino acids as systemic mediators of brain homeostasis against neurodegenerative processes.

GO Prime with only $1.49 now

LATEST
World Vaccine Congress Washington 2025 Recap: Urgent Calls for Trust, Tech, and Global Access
2025-04-25
Astellas’ Transformation Journey: From Merger to Global Player, Betting on the Edge of Innovation and Risk?
2025-04-25
Roche Announces Massive 50 Billion Dollar Investment in the United States
2025-04-25
Steminent Stands Ready to Showcase Novel MSC-based Therapy for Spinocerebellar Ataxia at Global Stage
2025-04-24
Arkansas Medicaid Work Requirements Led to Coverage Loss for a Significant Number of Recipients
2025-04-24
Boehringer agrees new partnership to advance first-in-class precision cancer therapies
2025-04-24
Bristol Myers Squibb Schizophrenia Drug Fails Pivotal Test as an Add-On to Antipsychotics
2025-04-24
EVENT
2025-04-25
AACR Annual Meeting 2025
Chicago, U.S.A
2025-05-03
29th Taiwan Joint Cancer Conference 2025
Taipei, Taiwan
2025-05-05
Swiss Biotech Day 2025
Basel, Switzerland
2025-05-13
ASGCT 28th Annual Meeting 2025
New Orleans, U.S.A.
2025-05-30
ASCO Annual Meeting 2025
Chicago, U.S.A
2025-06-11
ISSCR 2025 Annual Meeting
Hong Kong
Scroll to Top