December 19, 2004: Icelandic Genetic Study Showed the Impact of Population Structure on Association Studies
Icelandic biopharmaceutical company deCODE genetics published a study deciphering the impact of population structure on association studies. The research published on Nature Genetics on December 19, 2004 was the first genetic analysis in a national scale. Examining population structure in the relatively homogenous Icelandic gene pool, researchers suggested that allele frequencies still differ notably among subpopulations and sampling strategies need to be considered carefully.
Reference
https://www.nature.com/articles/ng1492
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