Empowering antibodies to better activate the immune system

**Study Examines Antibody Ratios in Activating Immune Cells Against HIV**

A recent study has analyzed how the ratio of antibodies to viral proteins impacts the activation of specific immune cells. Researchers at Scripps Research investigated this relationship, focusing on how antibodies interact with components of the immune system to combat infections. The findings were published on April 22, 2025, in *Cell Reports*.

The study centered on a segment of the HIV virus and revealed that a higher proportion of antibodies relative to viral protein enhances engagement with two types of immune cells. These cells play a role in clearing infections after being activated by antibodies. The research highlights factors that influence antibody effectiveness beyond their ability to neutralize pathogens directly, shedding light on their broader role in immune system activation.

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Source: https://www.worldpharmanews.com/research/6823-empowering-antibodies-to-better-activate-the-immune-system

Author

Mark Chiang