Genes Linked to Brain Aging and Drugs That May Target Them

Researchers have identified seven genes associated with accelerated biological brain aging and pinpointed 13 existing drugs that could potentially target these genes. The findings, published in *Science Advances*, stem from an analysis of MRI data stored in the UK Biobank.

The study utilized deep learning techniques to examine brain imaging data and genetic information from the UK Biobank, a large-scale biomedical database. Through this approach, scientists identified specific genes linked to faster brain aging processes. Additionally, they highlighted 13 drugs already in existence that may interact with these genetic targets. The research provides insights into the biological mechanisms underlying brain aging and suggests avenues for further investigation into potential therapeutic interventions.

Date: March, 2025

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Author

Mark Chiang