German Man Achieves HIV Remission After Stem Cell Transplant Using CCR5-Delta32 Donor Cells

A 60-year-old man from Germany has achieved sustained remission of HIV following a stem cell transplant, marking the seventh known case of its kind. The details of this medical development were published in the journal *Nature* this week. The patient, who was undergoing treatment for leukemia, received a stem cell transplant from a donor with a rare genetic mutation that provides resistance to HIV infection.

The report highlights that the patient has shown no detectable traces of HIV in his body since the procedure. This outcome follows similar cases where individuals with both cancer and HIV have undergone transplants using cells from donors with the CCR5-delta32 mutation, which blocks HIV from entering cells. Scientists continue to study these cases to better understand how such treatments may contribute to long-term remission or potential cures for HIV.

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Date: December 2, 2025

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