Groundbreaking Study Reveals Universal Mathematical Framework for Brain’s Spatial Mapping

A groundbreaking study led by Professor Yoram Burak from the Edmond and Lily Safra Center for Brain Sciences and the Racah Institute of Physics at the Hebrew University of Jerusalem has introduced a unifying mathematical framework that explains how “place cells” in the hippocampus encode spatial information. This discovery transcends species and environmental settings, providing significant insights into cognitive processes.

Place cells are specialized neurons in the brain’s hippocampus that enable navigation by forming a cognitive map of one’s environment. The research conducted by Prof. Burak and his team suggests that these cells operate under a universal mathematical model, which could explain their functionality across different species and varied environments.

This pioneering study not only enhances our understanding of spatial representation in the brain but also opens new avenues for investigating cognitive functions in health and disease.

Date: February 24, 2025

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Author

Mark Chiang

Ph.D in Biomedical Informatics Head of AI at GeneOnline