Kanazawa University Researchers Develop qMaLioffG to Quantitatively Image ATP Levels in Living Cells

Researchers at the Nano Life Science Institute (WPI-NanoLSI) at Kanazawa University have developed a method for quantitatively imaging adenosine triphosphate (ATP) levels within living cells. The study, published in *Nature Communications*, presents qMaLioffG, a genetically encoded fluorescence lifetime indicator that enables real-time observation of cellular energy production and consumption.

The newly introduced qMaLioffG technology uses fluorescence lifetime measurements to monitor ATP dynamics inside cells. ATP is a critical molecule responsible for storing and transferring energy in biological systems. By employing this innovative approach, scientists can track how cells generate and utilize energy under various conditions. This advancement provides researchers with the ability to study cellular processes more precisely, offering insights into metabolic activity and energy regulation mechanisms.

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Date: December 2, 2025

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