LncRNAs: Non-Coding RNAs Over 200 Nucleotides Regulate Gene Expression and Show Promise in Pediatric Brain Disorder Research

Long non-coding RNAs (lncRNAs) are now understood to be key regulators of gene expression, despite their initial obscurity. These RNA molecules, which are longer than 200 nucleotides and do not code for proteins, are now recognized as vital in managing complex biological processes.

LncRNAs play a role in the early stages of development, influencing cell differentiation, and maintaining tissue homeostasis. Researchers are actively exploring their potential as biomarkers and therapeutic targets, particularly in pediatric brain disorders. This is because lncRNAs have been found to be involved in neurodevelopmental disorders, brain tumors, and neurodegenerative diseases that affect children.

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Date: May 4, 2026

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GOAI