Nanoparticle-Based Vaccine Prevents Tumor Formation in Up to 88 Percent of Mice Across Multiple Cancer Types

Researchers at the University of Massachusetts Amherst have developed a nanoparticle-based vaccine that has shown significant success in preventing multiple types of cancer in mice. The study found that the vaccine effectively protected against melanoma, pancreatic cancer, and triple-negative breast cancer. Depending on the type of cancer, up to 88% of vaccinated mice remained tumor-free. Additionally, the vaccine demonstrated the ability to reduce or completely prevent metastasis, the spread of cancer to other parts of the body.

The findings highlight promising results across different forms of aggressive cancers. In trials conducted on mice, researchers observed that the vaccine not only inhibited tumor formation but also curtailed cancer’s progression in cases where it had already developed. The study suggests potential for further exploration into nanoparticle-based immunization strategies as a means to combat both primary tumors and metastatic disease.

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Date: October 9, 2025

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Author

Mark Chiang