NAPOLI-3 Trial Explores NALIRIFOX Efficacy and Pharmacist Strategies for Managing mPDAC Treatment Toxicities

The NAPOLI-3 trial has provided significant insights into the use of NALIRIFOX for treating metastatic pancreatic ductal adenocarcinoma (mPDAC). Vincent Chung, MD, shared key findings from the study and highlighted strategies for pharmacists to manage treatment-related toxicities, adjust dosing protocols, and support patients undergoing this therapy. The trial examined the efficacy and safety of NALIRIFOX in comparison to other treatment regimens, offering valuable data on its role in addressing mPDAC.

Dr. Chung emphasized the importance of pharmacist involvement in optimizing patient care during NALIRIFOX treatment. He outlined approaches for mitigating common toxicities associated with the regimen and discussed methods for tailoring dosages based on individual patient needs. Additionally, he stressed the need for comprehensive patient support systems to address challenges related to adherence and overall well-being during therapy. These findings aim to enhance clinical outcomes and improve quality of life for individuals battling metastatic pancreatic ductal adenocarcinoma.

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Source: GO-AI-ne1

Date: June 5, 2025

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Author

Mark Chiang