November 18, 2012: Skin Cells Reveal DNA’s Genetic Mosaic, Reported by Yale University
Yale Child Study Center released a new study showing that somatic cells of human are not completely identical even in one individual. The researchers observed numbers of variations from skin cells which have developed from the same mature-differentiated cell; humans are made up of a mosaic of cells with different genomes. In the skin, at least 30 percent of skin cells harbor copy number variations (CNV), which are segments of DNA that are deleted or duplicated. This finding shaped the future genetic study and sequencing technology, and demontrated uniqueness of every cell in an individual organism.
Reference
http://news.yale.edu/2012/11/18/skin-cells-reveal-dna-s-genetic-mosaic
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http://news.yale.edu/2012/11/18/skin-cells-reveal-dna-s-genetic-mosaic