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2025-04-14|

Oral Drug Imlunestrant Under Investigation: Degrades Estrogen Receptors and Penetrates the Brain

by Mark Chiang
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A new investigational drug, imlunestrant, is currently under development as a potential treatment option. Researchers are studying imlunestrant, an oral medication, for its ability to selectively degrade estrogen receptors and penetrate the brain. Specifically, scientists designed imlunestrant to target and break down estrogen receptors within the body. The drug is administered orally, and early research indicates it can cross the blood-brain barrier, allowing it to reach the brain. The drug’s mechanism of action involves selectively degrading estrogen receptors, which are proteins that play a role in various biological processes.

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Date: April 14, 2025

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