Role of Fatty Acids in Therapy Resistance for Triple-Negative Breast Cancer

A recent study published in the journal Immunity has identified a mechanism by which triple-negative breast cancer (TNBC) evades treatment. Researchers found that fatty acids play a role in promoting immune suppression and resistance to therapies commonly used to treat this aggressive form of breast cancer.

The findings highlight how TNBC cells utilize fatty acids to suppress the body’s immune response, creating an environment that allows tumors to grow unchecked and resist therapeutic interventions. The study provides evidence that these fatty acids contribute to the tumor’s ability to evade detection and destruction by the immune system, complicating efforts to manage the disease effectively. Researchers suggest this discovery could inform future approaches aimed at overcoming therapy resistance in TNBC patients.

Date: March, 2025

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Author

Mark Chiang

紐約 NYU Computer Science 碩士 紐澤西 UMDNJ Biomedical Informatics 博士 中研院博士後 台灣大學博士後