GENE ONLINE|News &
Scientists Successfully Use Gold-Nanoparticles to Deliver Novel Therapy for Brain Tumor
In a recent publication in the Journal Science Translational Medicine, scientists from Northwestern University in Chicago used gold nanoparticles to deliver small interfering RNA (siRNA) against the Bcl2L12 oncogene. The study demonstrated in non-human primates, and in a small proof-of-concept clinical trial that the treatment can be safely administered, it travels to the brain and into the tumors. Importantly, the nanoparticles reduced the levels of Bcl2L12 and caused an increase in proteins associated with cell death.
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