Specific Antibiotics May Alter CAR T-Cell Therapy Efficacy and Side Effects, Study Finds

Researchers have identified that particular antibiotics potentially influence the effectiveness and adverse effects of CAR T-cell therapy. The research focuses on observing the impact various antibiotics have on this cancer treatment. The study indicates that not all antibiotics are equal in their interaction with CAR T-cell therapy. Specific antibiotics could alter the way CAR T-cells function, potentially affecting how well they target and destroy cancer cells. Furthermore, these interactions might also influence the severity of side effects experienced by patients undergoing CAR T-cell treatment. The findings highlight the importance of considering the choice of antibiotics when managing infections in patients receiving CAR T-cell therapy.

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Date: April 28, 2025

Author

Mark Chiang