Study Finds Pregnancy Causes Lasting Changes in Mouse Intestine

A recent study conducted by researchers at the Francis Crick Institute has revealed that pregnancy triggers growth in the small intestine of mice, resulting in changes that are partially irreversible. The findings suggest these alterations may assist mice in sustaining a pregnancy and preparing for subsequent ones.

The research observed that during pregnancy, the small intestine undergoes structural remodeling, increasing its capacity to absorb nutrients. This adaptation likely supports the heightened nutritional demands of gestation. Notably, some of these changes persist even after the pregnancy ends, indicating a long-term physiological adjustment. The study highlights how pregnancy not only impacts reproductive organs but also prompts lasting modifications in other parts of the body to accommodate reproductive needs. Researchers believe this discovery could provide insights into how mammals adapt to reproduction-related challenges.

Date: March, 2025

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Author

Mark Chiang

紐約 NYU Computer Science 碩士 紐澤西 UMDNJ Biomedical Informatics 博士 中研院博士後 台灣大學博士後