Study Links Poor Sleep in Older Adults to Glymphatic System Disruption

A recent study has identified a connection between poor sleep quality in older adults and dysfunction in the brain’s glymphatic system, which is responsible for clearing waste and toxins. Researchers observed that disrupted sleep patterns impair this vital system, potentially contributing to memory decline and cognitive impairments.

The glymphatic system operates primarily during sleep, removing harmful substances from the brain. The study highlights that when sleep quality is compromised, this waste-removal process becomes less effective. This dysfunction may lead to an accumulation of toxins associated with neurological issues. The findings suggest a possible link between insufficient sleep and increased risks of cognitive decline as individuals age. Researchers emphasize the importance of understanding how sleep impacts brain health, particularly in older populations.

Date: March 11, 2025.

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Author

Mark Chiang

Ph.D in Biomedical Informatics Head of AI at GeneOnline