Study Links Pupil Size to Brain Activity During Sleep

A pioneering study has uncovered a fascinating connection between pupil size and brain activity during sleep. Researchers have found that pupils continue to fluctuate in size throughout the sleep cycle, mirroring changes in brain activation levels. This discovery sheds new light on the intricate dynamics of the sleeping brain.

The research team developed an innovative method to observe these fluctuations without disrupting sleep. By keeping participants’ eyes open during testing, scientists were able to monitor pupil size changes with precision while ensuring natural sleep patterns remained intact.

This breakthrough could pave the way for deeper insights into how brain activity evolves during different stages of sleep and may hold implications for understanding neurological conditions or optimizing sleep health.

Date: March 5, 2025

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Author

Mark Chiang

Ph.D in Biomedical Informatics Head of AI at GeneOnline