Sulodexide Reduces Sepsis-Related Lung Injury in Neonatal Rats by Modulating TNF-α Pathway

A study published in the journal *Pediatric Research* indicates that the antithrombotic agent sulodexide reduces lung injury associated with sepsis in neonatal rats. Researchers observed that the medication influences the tumor necrosis factor-alpha (TNF-α) pathway, which serves as a primary mediator in inflammatory responses.

The investigation focused on how sulodexide interacts with biological processes during neonatal sepsis. By modulating the TNF-α pathway, the treatment appears to limit the severity of lung damage in the test subjects. These findings provide data on the potential role of antithrombotic agents in addressing inflammatory complications in newborns.

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Source: GO-AI-ne1

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Date: June 2, 2026

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GOAI