GeneOnline sat down with Hsin-Chiao Chou (Ilsa Chou), Postdoctoral Fellow at China Medical University, to talk about some exciting new approaches for metastatic triple-negative breast cancer (TNBC).
Ilsa explained how their team is targeting DDB2, a protein that helps tumor cells repair damaged DNA and resist drugs. Their new therapy, NuPlus, works as a DDB2 degrader, essentially stopping cancer cells from fixing themselves. Early data shows it’s both effective and safe, even with repeated doses.
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