6 March, 2014: First time Scientist gene-editing Immune Cells Successful, open a new treatment possibility for AIDS

A research team from the Perelman School of Medicine, University of Pennsylvania, enrolled 12 patients in an uncontrolled study of a single dose of ZFN-modified autologous CD4 T cells. The patients had the chronic aviremic HIV infection while they were receiving highly active antiretroviral therapy. After the infusion of 10 billion autologous CD4 T cells, the blood level of HIV DNA decreased in most patients. This study was a milestone for gene-editing technology application on fatal disease treatment.

Reference
http://www.nejm.org/doi/full/10.1056/NEJMoa1300662

Image Source
https://en.wikipedia.org/wiki/HIV

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