GENE ONLINE|News &
Researchers Engineer “Mini” CRISPR-Cas System That Could Act as ‘Swiss Army Knife’ for Mammalian Genome Editing
A team of researchers at Stanford University have engineered a highly compact and versatile CRISPR-Cas system for mammalian genome editing and regulation, which is less than half the size of currently used CRISPR Cas9 or Cas12a systems. Strikingly though, they have levels of gene activation comparable to that of Cas12a.
The scientists believe that its diminutive size would facilitate high-efficiency transport for a wide range of genome engineering applications that require the delivery of compact Cas-fusion proteins for varied cellular functions.
In a recent report published in Molecular Cell, the researchers state that this engineered, efficient, specific, compact, versatile, and multi-purpose “mini” CRISPR-Cas system could serve as a “Swiss Army knife” in mammalian genome editing.
The scientists believe that its diminutive size would facilitate high-efficiency transport for a wide range of genome engineering applications that require the delivery of compact Cas-fusion proteins for varied cellular functions.
In a recent report published in Molecular Cell, the researchers state that this engineered, efficient, specific, compact, versatile, and multi-purpose “mini” CRISPR-Cas system could serve as a “Swiss Army knife” in mammalian genome editing.
GO Prime with only $1.49 now
LATEST
Novo Nordisk Revises Outlook: Reports 24% Growth in Q1 2024 Sales, Reaching DKK 65.3 Billion
2024-05-03
UC Riverside Scientists Unveil RNA-based Vaccine Strategy, Potentially Avoiding Endless Booster Shots
2024-05-02
Lilly’s Q1 2024 Financial Report: Full-Year Revenue Outlook Raised by $2 Billion, with a 67% Net Income Increase
2024-05-02
Taiwan Breakthrough: Next-Generation Sequencing Now Covered in Health Insurance, Benefitting 20,000 Cancer Patients Annually
2024-05-02
