GENE ONLINE|News &
Opinion
Blog

2021-01-16| Asia-PacificR&D

Takeda, KSQ Join Forces to Identify NK Cell Targets For Cancer Therapies

by Tyler Chen
Share To

Cancer therapy without a doubt will be one of the most trending topics in 2021. As several contenders push their way into the field, on January 13, Japanese biopharma, Takeda joined forces with US based KSQ Therapeutics to develop, manufacture and commercialize immuno-oncology therapies.

 

This strategy fits Takeda’s long-term growth plan on creating innovative therapies on 5 chosen areas, which is Gastroenterology (GI), Rare Diseases, Plasma-Derived Therapies, Oncology, and Neuroscience.

 

T-cell and NK cells for New Cancer Treatments

 

The collaboration will mainly involve the two T-cell targets identified and validated by KSQ Therapeutics, with the potential of two additional T-cell targets. In addition, Takeda will utilize KSQ’s CRISPRomics discovery platform to screen the whole human genome to spot natural killer (NK) cell targets for autoimmune and oncology therapeutics.

 

“KSQ’s CRISPRomics discovery platform is a powerful technology to help us identify novel targets in line with our immuno-oncology strategy,” said Loïc Vincent, Head, Oncology Drug Discovery Unit and Immunology Unit at Takeda.

He further stated, “The T-cell and NK-cell target discovery approach complements our portfolio aimed at turning cold tumors hot and redirecting the innate immune system to elicit a sustained and durable immune response against tumors”.

 

Details of Collaboration

 

Takeda will offer 100 million upfront and preclinical milestone payments and up to 400 million each for development and commercialization milestones in exchange of an exclusive, worldwide, royalty-bearing license to develop, manufacture and commercialize cell and non-cell therapy products.

 

While Takeda lead the clinical development of IND-enabling activities with KSQ and also pay for expenses in the process, KSQ is able to assume responsibility in one of the two T-cell targets, sharing cost and profit of the process and retain royalties on all ex-U.S. sales for that product.

 

Related Article: China’s Hasten Biopharmaceutic Acquires Five Non-Core Assets from Japan’s Takeda

 

References

1. https://www.businesswire.com/news/home/20210113005121/en/

 

©www.geneonline.com All rights reserved. Collaborate with us: service@geneonlineasia.com
Related Post
AstraZeneca’s $1.5 Billion ADC Manufacturing Facility in Singapore
2024-05-23
Taiwan Breakthrough: Next-Generation Sequencing Now Covered in Health Insurance, Benefitting 20,000 Cancer Patients Annually
2024-05-02
Takeda, Astellas, and Sumitomo Mitsui Banking Declare Agreement For Early Drug Discovery Program Incubation in Joint Venture
2024-04-23
LATEST
New Regulatory Measures in China A First in the Fight Against Sedentary Behavior in Children
2024-05-24
Cure Genetics Announced Promising Safety and Efficacy Data of CAR-NKT Product CGC729 for RCC at ASGCT 2024
2024-05-23
AstraZeneca’s $1.5 Billion ADC Manufacturing Facility in Singapore
2024-05-23
Hims & Hers Health Inc. Tipping the Scales of the Weight Loss Market — and Wall Street is Loving it!
2024-05-22
GV Announces Cooperation with CICC
2024-05-22
Eli Lilly and Aktis Oncology Partner to Advance Novel Radiopharmaceuticals
2024-05-22
Preventive Medicine for Neurodegeneration on the Rise: New Breakthrough in Routine Blood Testing for Alzheimer’s Disease
2024-05-20
EVENT
Scroll to Top